Primary intraocular posttransplantation lymphoproliferative disorder.
نویسندگان
چکیده
We report a case of posttransplantation lymphoproliferative disorder manifesting as an isolated, unilateral iris tumor. A 2-year-old boy who had undergone liver transplantation for biliary atresia at age 4 months was seen with a 2-month history of an enlarging iris nodule. Histopathologic examination of the iris lesion demonstrated a mixed population of lymphoid cells. To our knowledge, this is the youngest patient with posttransplantation lymphoproliferative disorder isolated to the eye.
منابع مشابه
Associations among Epstein-Barr virus subtypes, human leukocyte antigen class I alleles, and the development of posttransplantation lymphoproliferative disorder in bone marrow transplant recipients.
The association between Epstein-Barr virus subtype, human leukocyte antigen class I alleles, and the development of posttransplantation lymphoproliferative disorder was examined in a group of 25 bone marrow transplant recipients. A highly statistically significant correlation was observed between the human leukocyte antigen B51 allele and development of posttransplantation lymphoproliferative d...
متن کاملA Rare Presentation of Isolated CNS Posttransplantation Lymphoproliferative Disorder
Posttransplantation lymphoproliferative disorder (PTLD) is a recognized and extremely morbid complication of solid organ transplantation, but central nervous system involvement, particularly in isolation, is rare. There are no standardized treatment strategies for PTLD, though commonly used strategies include reduction of immunosuppression, chemotherapy, rituximab, radiation, and surgery. We pr...
متن کاملNew developments in the diagnosis and management of posttransplantation lymphoproliferative disorders in solid organ transplant recipients.
Posttransplantation lymphoproliferative disorders (PTLDs) have emerged as important causes of morbidity and mortality in solid organ transplant recipients. Epstein-Barr virus (EBV) plays a major pathophysiologic role in the development of many, if not most, of the highly diverse disease states, which span the spectrum from infection to malignancy, encompassed by the term "PTLD." Clinical presen...
متن کاملEBV and posttransplantation lymphoproliferative disease: what to do?
This review summarizes the available evidence and outlines our approach to the prophylaxis and management of posttransplantation lymphoproliferative disorder (PTLD) in adult solid organ transplantation recipients. We attempt to reduce immunosuppression as tolerated in every patient with suspected PTLD in close cooperation with their transplantation physician. There is no evidence to guide the d...
متن کاملMagnetic Resonance Imaging Findings of Posttransplantation Lymphoproliferative Disorder in Liver and Renal Allograft: a case report
Posttransplantation lymphoproliferative disorder (PTLD) represents a spectrum of Epstein-Barr virus (EBV)-driven lymphoid proliferation related to immunosuppressive therapy. We here report a case of a 21-year-old male with PTLD of liver and renal allograft simultaneously after renal transplantation. MRI depicted solid mass lesions, which were hypointense on T1-weighted images and heterogeneousl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of ophthalmology
دوره 116 12 شماره
صفحات -
تاریخ انتشار 1998